PT-141（10 VIALS / BOX）

Synthetic Peptide for Melanocortin Receptor Research

Technical Overview

PT-141 10mg is a synthetic peptide compound developed for laboratory research involving melanocortin signaling and central neuroendocrine pathways, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying MC3R and MC4R receptor binding, downstream cAMP signaling in hypothalamic models, and related biochemical mechanisms.

PT-141 (bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH) featuring a side-chain lactam bridge between Asp and Lys, N-terminal acetylation, and incorporation of norleucine and D-phenylalanine for protease resistance. It is a non-selective agonist of MC1R, MC3R, MC4R, and MC5R with preferential activity at MC3R/MC4R.

Researchers use PT-141 to investigate central melanocortin signaling, sexual-behavior circuits in rodent models, and receptor-selectivity comparisons against alpha-MSH and NDP-MSH. Its protease-resistant structure makes it a stable reference compound for melanocortin receptor pharmacology.

This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.

Specifications

Compound Name: PT-141
Strength: 10mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.

Notice

Provided as a reference material for scientific investigation only.